The Los Angeles Chargers and Washington Commanders enter Week 5 on similar footing—both are coming off losses with something to prove. Each has handled its business at home but stumbled on the road. On Sunday, only one can keep pace with their early-season playoff aspirations.
Commanders vs Chargers Odds

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Odds via DraftKings Sportsbook
- Spread: Commanders +2.5 (-105) | Chargers -2.5 (-105)
- Moneyline: Commanders +120 | Chargers -142
- Total: 47.5 (Over -110/Under -110)
Game Details
- Date: Sunday, Oct. 5
- Time: 4:25 p.m. ET
- Venue: SoFi Stadium
- TV: FOX
Betting Trends
- Washington is 2-2 against the spread but 0-2 ATS on the road.
- Los Angeles is 2-1-1 ATS overall and unbeaten ATS at home (1-0-1).
- The Commanders have split totals (2-2 to the under/over).
- The Chargers lean under, with three of four games staying below the total.
Injury Watch

- Commanders: QB Jayden Daniels (questionable), Percy Butler (questionable), Noah Brown (questionable), John Bates (questionable).
- Chargers: Joe Alt, Mekhi Becton.
Daniels’ status looms large. If he returns, Washington gains a dynamic rushing element that has caused defenses headaches early in the season.
Key Player to Watch: Justin Herbert
Quarterback Justin Herbert opened the year with precision—560 yards, five touchdowns, and zero interceptions in his first two outings. Since then, things have cooled. His completion percentage dipped below 60% the past two weeks, with just two touchdowns against three interceptions, including two costly giveaways against the Giants.
This matchup offers a get-right opportunity. Washington’s secondary has been generous, surrendering at least 289 passing yards and multiple scores in three straight games. If Herbert is sharp, his trio of receivers and rookie back Omarion Hampton give him the tools to put up points in bunches.
Why the Commanders Can Cover
Washington’s offensive line has been battered, yet Daniels’ potential return adds unpredictability. Before missing Week 4, the Commanders ranked third in rushing offense DVOA. Against a Chargers defense that just gave up 161 yards on the ground to the Giants, Daniels’ mobility could tilt things.
There’s also the matter of the Chargers’ health up front. Rookie tackle Joe Alt left last week’s game with an ankle injury, and Mekhi Becton is still nursing his own ailment. If both miss Sunday, Herbert may be forced into rushed throws—never ideal against a defense that thrives on opportunistic playmaking.
History also suggests trouble if Los Angeles allows points in bunches. Per Evan Abrams of The Action Network, Herbert is just 11-25 against the spread when his defense surrenders 24 or more points.
Why the Chargers Should Prevail

Jesse Minter’s defense hasn’t allowed more than 21 points in a game this season. At home, the Chargers have toppled the Chiefs and Broncos with relative control. Add in the Commanders’ road woes (0-2 both straight up and ATS), and Los Angeles holds a situational edge.
Herbert also has statistical history on his side. Washington’s secondary has already been diced by Jordan Love, Geno Smith, and Michael Penix Jr.—all of whom topped 289 yards with multiple touchdowns. Herbert is a step above that group in arm talent.
Prediction and Best Bet
This game boils down to quarterback play. If Daniels is healthy and effective, Washington’s run-pass option attack can challenge the Chargers’ front seven. But if he’s limited, the Commanders don’t have enough weapons to keep pace with Herbert in Los Angeles.
Expect the Chargers to lean on Hampton, who has emerged as a versatile threat, and for Herbert to rebound against a leaky Washington secondary.
Final Score Prediction: Chargers 29, Commanders 23
Best Bet: Chargers -2.5 (-105) | Lean Over 47.5
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