The Los Angeles Rams are gearing up for the 2025 NFL season, and the path ahead looks both promising and challenging. With a mix of powerhouse matchups and division rivalries on deck, the Rams will be tested as they attempt to defend their NFC West title.
Their slate of opponents includes not just the always-competitive NFC West—Seattle Seahawks, San Francisco 49ers, and Arizona Cardinals—but also several high-caliber teams from other divisions. Among the most notable opponents are the Philadelphia Eagles, Baltimore Ravens, Detroit Lions, and Tampa Bay Buccaneers, all of whom were either playoff contenders or division winners last season.
Los Angeles Rams 2025 Strength Of Schedule

According to Sharp Football Analysis, the Rams face the 13th-hardest schedule in the NFL for 2025 based on projected win totals from Vegas oddsmakers. This approach, which uses betting market projections rather than previous season win-loss records, offers a more forward-looking measure of schedule difficulty.
Los Angeles enters the year with momentum, having reclaimed the NFC West crown in 2024. However, repeating as division champs will require navigating a schedule stacked with potential playoff teams. The Rams will also see several non-conference matchups that will serve as important litmus tests for their postseason aspirations.
The NFL will release the full 2025 schedule on May 14, detailing exact dates and times. But until then, here’s a breakdown of the Rams’ confirmed opponents and their oddsmaker over/under win total:
The Rams over/under is set a 9.5 games
Home Games
- San Francisco 49ers: 10.5
- Detroit Lions: 10.5
- Tampa Bay Buccaneers: 9.5
- Houston Texans: 9.5
- Arizona Cardinals: 8.5
- Seattle Seahawks: 7.5
- Indianapolis Colts: 7.5
- New Orleans Saints: 6.5
Away Games
- Philadelphia Eagles: 11.5
- Baltimore Ravens: 11.5
- San Francisco 49ers: 10.5
- Arizona Cardinals: 8.5
- Seattle Seahawks: 7.5
- Atlanta Falcons: 7.5
- Jacksonville Jaguars: 7.5
- Carolina Panthers: 6.5
- Tennessee Titans: 5.5
As the Rams prepare for training camp, all eyes will be on how head coach Sean McVay and his roster respond to what projects to be a demanding campaign. With several playoff-caliber opponents on the schedule and a competitive NFC West standing in their way, the 2025 season will be a true test of Los Angeles’s depth, resilience, and postseason potential.
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