One of the most intriguing matchups in the first half of the 2025 NFL season will come in Week 5, when the Washington Commanders face off against the Los Angeles Chargers. While both teams bring firepower on offense, one of the key storylines will be a reunion of former college teammates: Chargers wide receiver Tre Harris and Commanders cornerback Trey Amos, who once battled daily in practice at Ole Miss.
This time, however, the stakes are far higher.
Ole Miss Teammates Will Square Off In Los Angeles Chargers Week 5
The Chargers’ offense, led by star quarterback Justin Herbert, is already dangerous with top targets Ladd McConkey and fellow rookie Omarion Hampton. McConkey is expected to draw more double teams after a breakout rookie year, which puts additional responsibility on Harris to step up. A big-bodied receiver with refined route-running skills and excellent ball control, Harris is well-positioned to become a vital part of L.A.’s aerial attack.
Across the line, Amos will be tasked with slowing him down. One of the most physical corners in the 2025 draft class, Amos thrives in press-man coverage. His instincts, toughness, and ability to disrupt timing routes make him a potential game-changer in Washington’s secondary.
This one-on-one showdown has all the makings of a highlight reel. The familiarity between Harris and Amos adds an extra layer of intrigue—these two know each other’s strengths and tendencies from their days at Ole Miss. Expect a chess match on the perimeter, as Harris tries to create separation and Amos aims to shut him down.
Beyond the personal rivalry, this game features two explosive offenses and promising rookie talents on both sides. If early signs hold true, the Week 5 clash between the Chargers and Commanders could be one of the most electric matchups of the 2025 season.
Subscribe to LAFB Network’s Los Angeles Chargers YouTube Channel